New Study Demonstrates BIOMEnd's Pharmacokinetic Benefits Over Tributyrin and Sodium Butyrate

January 21st, 2025, East Setauket, NY – NutraShure Distribution, LLC. (“NutraShure”), a premium ingredient supplier in the dietary supplement and functional food and beverage categories shared today its groundbreaking study published in the Journal of Exercise and Nutrition: A Pharmacokinetic Comparison of Three Butyrate Products. The study provides new insights into the pharmacokinetics and physiological effects of three butyrate forms – sodium butyrate (NaB), lysine butyrate (as BIOMEnd™) (LysB), and tributyrin (TB).

The study included healthy adult men, aged 25-45, who ingested one of three butyrate forms, with blood samples and assessments collected over a 3.5-hour post-ingestion period. Measurements included serum butyrate concentrations, feelings of well-being, and physiological vitals. Blood samples were collected at six time points and analyzed using advanced GC-MS techniques to measure serum butyrate levels. In addition, Visual Analog Scales (VAS) evaluated participants’ well-being, mood, motivation, and concentration at multiple time points.

The results showed BIOMEnd, a STACK3D top innovation of 2024, had significantly higher peak plasma concentrations (Cmax) and quicker time to maximum concentration (Tmax) compared to tributyrin – indicating its superior bioavailability and faster systemic circulation. In addition, participants reported improved feelings of well-being, calmness, and motivation after ingesting BIOMEnd. Notably, BIOMEnd achieved 500% greater Cmax than tributyrin and 180% greater Cmax than sodium butyrate.  The results emphasize BIOMEnd’s efficacy in delivering butyrate into the bloodstream more effectively than current forms on the market.

“This study is the first comparative study of three commercially available forms of butyrate,” said Brandon Sojka, CEO at NutraShure. “The exceptional pharmacokinetic advantage of BIOMEnd coupled with our new substantiated GLP-1 claims and superior delivery form allows us to provide a truly innovative solution for supporting gut health, weight management, and overall well-being.”

BIOMEnd is a superior form of butyrate, delivering benefits to solve ongoing palatability and solubility issues seen with traditional butyrate ingredients currently on the market. Designed with both formulators and consumers in mind, BIOMEnd delivers superior benefits for gut health, GLP-1 support, and immune health without the unpleasant taste often associated with other butyrate products on the market.

About NutraShure Distribution, LLC.

NutraShure Distribution, LLC. is a premium ingredient supplier for use in dietary supplements, functional foods, and beverages. NutraShure set out with the goal of optimizing human performance and increasing the overall quality of daily life. NutraShure Distribution offers ingredients with a wide range of health benefit categories with patent-protected IP and preclinical and clinical research. These categories include sports nutrition, men’s health, gut health, weight management, immune health, and more.